上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (9): 1347-.doi: 10.3969/j.issn.1674-8115.2011.09.032

• 短篇论著 • 上一篇    下一篇

后负荷对Sarns2000离心泵溶血情况的影响

韩 露1,2, 王 伟1,2, 俞晓青1, 丁文祥1   

  1. 上海交通大学 医学院附属上海儿童医学中心 1.心胸外科, 2.儿科转化医学研究所, 上海 200127
  • 出版日期:2011-09-28 发布日期:2011-09-27
  • 通讯作者: 王 伟, 电子信箱: wangweicpb@yahoo.com。
  • 作者简介:韩 露(1984—), 女, 助理工程师, 硕士；电子信箱: hlrain0621@163.com。
  • 基金资助:

    浦东新区科技发展基金创新资金 (PKJ2010-Y30)

Effect of afterload pressure on hemolytic blood damage in Sarns2000 centrifugal pump

HAN Lu1,2, WANG Wei1,2, YU Xiao-qing1, DING Wen-xiang1   

  1. 1. Department of Cardiovascular and Thoracic Surgery, 2. Institute of Pediatric Translational Medicine, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2011-09-28 Published:2011-09-27
  • Supported by:

    Foundation of Development and Innovation of Science and Technology of Pudong New Area, Shanghai, PKJ2010-Y30

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摘要：

目的 探讨离心泵后负荷压力对血液破坏的影响。方法 采用计算流体仿真（CFD），实现Sarns2000离心血泵的数值分析。对比分析该泵有后负荷工况和空载状态时泵内液体流速、压力、剪切力的差异。结果 在1 400 r/min转速下，有后负荷时流速降低，泵的流量降低。泵内压力增大，溶血破坏增加；但剪切力大于150 Pa的区域小于0.000 032%，对溶血的控制较好。结论 后负荷压力会导致Sarns2000离心泵内溶血破坏的概率增加，但不会出现因剪切力导致大量溶血的问题。

关键词: 计算流体仿真, 离心式血泵, 数值模拟, 溶血

Abstract:

Objective To investigate the effect of afterload pressure on hemolytic blood damage in centrifugal pump. Methods The differences between velocity, pressure and surface shear force of the internal flow of Sarns2000 centrifugal pump with afterload pressure and those without afterload pressure were obtained by computational fluid dynamics(CFD). Results The velocity and flow of pump deceased when the rotational speed was 1 400 r/min with afterload pressure. The hemolytic blood damage increased with the pressure increase in the pump. However, the area whose surface shear force was greater than 150 Pa was less than 0.000032%, which had a good performance of hemolysis. Conclusion The afterload pressure would enhance the possibility of hemolysis in Sarns2000 centrifugal pump, while the surface shear force has a good performance of hemolysis.

Key words: computational fluid dynamics, centrifugal pump, numerical simulation, hemolysis