上海交通大学学报（医学版）

›› 2012, Vol. 32 ›› Issue (9): 1209-.doi: 10.3969/j.issn.1674-8115.2012.09.016

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睡眠对儿童生长发育影响的研究及其应用

沈晓明, 江 帆, 李生慧, 颜崇淮, 田 英, 吴增强, 陈文娟, 丁 瑜, 金星明, 吴 皓   

  1. 教育部-上海环境与儿童健康重点实验室 睡眠与儿童健康项目组, 上海 200092
  • 出版日期:2012-09-28 发布日期:2012-09-29
  • 作者简介:沈晓明(1963—), 男, 教授, 博士, 博士生导师, 现任中华医学会常务理事、中华预防医学会儿童保健学会名誉主任委员；电子信箱: xmshen@shsmu.edu.cn。
  • 基金资助:

    国家重点基础研究发展计划(“九七三”计划)(2010CB535000)；国家自然科学基金(30271373, 30500410, 30700670, 81172685)；上海市科委重点项目（994119012）；上海市科委启明星计划(10QA1404800)；上海市教委曙光计划(11SG19)；上海市教委学生健康促进工程重大决策咨询课题（HJTY-2010-A09）；教育部新世纪优秀人才培养计划

Study on the effect of sleep on children´s growth development and its application

SHEN Xiao-ming, JIANG Fan, LI Sheng-hui, YAN Chong-huai, TIAN Ying, WU Zeng-qian, CHEN Wen-juan, DING Yu, JIN Xing-ming, WU Hao   

  1. Ministry of Education-Shanghai Key Laboratory of Environmental Child Health, Sleep and Child Health Research Group, Shanghai 200092
  • Online:2012-09-28 Published:2012-09-29

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摘要：

睡眠对儿童来说，不仅有保障机体复原的作用，同时还有调控体格生长与学习记忆的功能。因此，睡眠关乎儿童健康成长乃至未来国民素质。然而，随着社会发展和生活节奏加快，人类睡眠时间不断减少，各种睡眠障碍发生率持续上升。这一现象激发了学术界对睡眠问题的广泛兴趣，睡眠医学应运而生，但国际上研究多局限于基础和临床医学领域。项目组于1996年始率先从流行病学、儿科学、神经生物学和教育学四个视角开展儿童睡眠跨学科研究，并以研究结果推动政府决策，保障了儿童睡眠健康,为国内首个儿童睡眠领域的系列研究，解答了以下4个问题：①我国儿童睡眠有无“质”和“量”上的问题；②这种问题对健康有什么危害；③这种危害是如何产生的；④如何预防这种危害。项目组通过流行病学、儿科学、神经生物学和教育学跨学科交叉研究，系统评价了我国儿童的睡眠状况及主要影响因素，填补了国内儿童睡眠基础资料的空白；以肥胖和学习记忆功能为切入点，探讨睡眠对儿童体格生长和神经系统发育的影响及其机制；从睡眠健康的角度对目前中小学校作息制度提出干预方案和政策建议，并推动政府决策，改变现行不合理的中小学校作息制度，保障儿童健康。项目组的研究成果在取得良好的社会效益的同时，也获得了一系列创新性学术成果,获2011年度国家科技进步二等奖。

关键词: 睡眠, 儿童, 肥胖, 学习记忆, 应用

Abstract:

Sleep plays an very important role in children´s growth and development, but insufficient sleep as well as sleep disorders turns to be common in modern society. This research project is the first series research in the field of sleep which was designed to address below questions. ①Chinese children´s sleep ever have “quality” and “quantity” problem? ②If those kinds of sleep problems affect children´s health? ③How these kinds of harm effect children’s health? ④How to prevent such hazards. This project was designed to carry out the systematic evaluation of children´s sleep and its related factors by multidisciplinary teams from epidemiology, pediatrics, neurobiology, and pedagogy. It was valued as filling the blank of national children sleep foundation information. In addition, it was further explored the effects and mechanism of sleep on children physical growth and nervous system development such as obesity and learning and memories. Finally, this study was translated into health policy to advocate the government postpone the school start time based on the results from well designed studies. From the perspective of sleep health, make policy recommendations and intervention programme on the current daily routine of primary and secondary schools. This policy was later proved to not only increase children´s sleep time but also improve their sleep quality. This was kind of translational research to use medical research results into health policy, eventually benefits children´s health. This research project obtained the National Scientific and Technological Progress Second Prize in 2011.

Key words: sleep, children, obesity, learning memory, application