上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2019, Vol. 39 ›› Issue (12): 1460-.doi: 10.3969/j.issn.1674-8115.2019.12.020

• 综述 • 上一篇    下一篇

经颅直流电刺激治疗单相和双相抑郁障碍的研究进展

黄雨欣，汤叶舟，赵雅娟，符 浩，王 勇，金 华   

  1. 上海交通大学医学院附属精神卫生中心门诊部，上海 200030
  • 出版日期:2019-12-28 发布日期:2020-02-06
  • 作者简介:黄雨欣（1996—），女，硕士生；电子信箱：huangyuxin499@mail.sjtu.edu.cn。
  • 基金资助:
    上海申康医院发展中心市级医院临床研究培育项目（SHDC12018X24）；“十三五”国家重点研发计划（2016YFC1307100）；上海市卫生和计划生育委员会科研课题-面上项目（201640107）；上海交通大学“医工(理)交叉基金”（YG2016MS39）

Progress of transcranial direct current stimulation in the treatment of unipolar and bipolar depressive disorders

HUANG Yu-xin, TANG Ye-zhou, ZHAO Ya-juan, FU Hao, WANG Yong, JIN Hua   

  1. Department of Outpatient, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2019-12-28 Published:2020-02-06
  • Supported by:
    Municipal Hospital Clinical Research and Cultivation Project of Shanghai Shenkang Hospital Development Center, SHDC12018X24; 13th Five-Year National Key R&D Program of China, 2016YFC1307100; General Program of Scientific Research Project of Shanghai Municipal Commission of Health and Family Planning, 201640107; Medical Engineering (Science) Cross Fund of Shanghai Jiao Tong University, YG2016MS39

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摘要： 经颅直流电刺激是一种有前景的治疗单相和双相抑郁障碍的非侵入物理刺激手段，其作用机制、治疗效果及最佳参数仍处于探索阶段。基于研究现状，该文针对tDCS在单相、双相抑郁发作的急性期和维持期的疗效及安全性进行了综述，并阐述了tDCS对于难治性抑郁障碍患者的疗效，为后续研究和临床应用提供了可能的思路。

关键词: 经颅直流电刺激, 电刺激, 抑郁障碍, 双相障碍, 物理治疗

Abstract:

Transcranial direct current stimulation (tDCS) is a promising non-invasive physical stimulation for the treatment of unipolar and bipolar disorders. Its mechanism, efficacy and optimal parameters are still in the exploration stage. Based on the tDCS-related researches of unipolar and bipolar disorders in recent years, this paper reviews the efficacy and safety of tDCS treatment in depressive acute stage and maintenance stage, and demonstrates the efficacy of tDCS on treatment-resistant depressive disorder patients, which provides possible ideas for follow-up research and clinical application.

Key words: transcranial direct current stimulation (tDCS), electrical stimulation, depressive disorder, bipolar disorder, physicotherapeutics