非侵入性脑刺激在抑郁障碍躯体症状治疗中的应用综述

doi:10.3969/j.issn.1674-8115.2021.11.021

摘要/Abstract

摘要：

抑郁障碍的躯体症状与病程、缓解率、临床症状严重程度相关。目前一线治疗方法为药物治疗，但药物的不良反应常与躯体症状相重叠。研究表明非侵入性脑刺激在抑郁障碍躯体症状的治疗上具有应用价值。该文综述了重复经颅磁刺激、经颅直流电刺激在抑郁障碍躯体症状治疗中的应用现状，阐述了这两类非侵入性脑刺激技术对抑郁障碍患者疼痛、失眠等躯体症状的疗效与现有研究的不足，并提出了后续研究的发展方向。

关键词: 非侵入性脑刺激, 抑郁障碍, 躯体症状, 重复经颅磁刺激, 经颅直流电刺激

Abstract:

The somatic symptoms of major depressive disorder are related to the course of disease, remission rate and severity of clinical symptoms. At present, the first-line treatment is drug therapy, but the adverse effects of drugs often overlap with somatic symptoms. The studies have shown that non-invasive brain stimulation has application values in the treatment of somatic symptoms in major depressive disorder. This paper reviews the current status of repetitive transcranial magnetic stimulation and transcranial direct current stimulation in the treatment of somatic symptoms of major depressive disorder. It also discusses the efficacy of these two types of non-invasive brain stimulation techniques in the treatment of pain and insomnia in the patients with major depressive disorder, as well as the shortcomings of the existing research, and proposes the developing direction of future research.

Key words: non-invasive brain stimulation, major depressive disorder, somatic symptom, repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS)

中图分类号:

R749.05

沈琳洁, 黄雨欣, 王勇, 金华. 非侵入性脑刺激在抑郁障碍躯体症状治疗中的应用综述[J]. 上海交通大学学报(医学版), 2021, 41(11): 1535-1539.

Lin-jie SHEN, Yu-xin HUANG, Yong WANG, Hua JIN. Review of non-invasive brain stimulation for the treatment of somatic symptoms in major depressive disorder[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(11): 1535-1539.

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