1 |
ZHANG S W, SUN K X, ZHENG R S, et al. Cancer incidence and mortality in China, 2015[J]. J Natl Cancer Cent, 2021, 1(1): 2-11.
|
2 |
GERSTBERGER S, JIANG Q W, GANESH K. Metastasis[J]. Cell, 2023, 186(8): 1564-1579.
|
3 |
PIUNTI A, SHILATIFARD A. The roles of Polycomb repressive complexes in mammalian development and cancer[J]. Nat Rev Mol Cell Biol, 2021, 22(5): 326-345.
|
4 |
LAUGESEN A, HØJFELDT J W, HELIN K. Molecular mechanisms directing PRC2 recruitment and H3K27 methylation[J]. Mol Cell, 2019, 74(1): 8-18.
|
5 |
SU W J, HAN H H, WANG Y, et al. The polycomb repressor complex 1 drives double-negative prostate cancer metastasis by coordinating stemness and immune suppression[J]. Cancer Cell, 2019, 36(2): 139-155.e10.
|
6 |
JUNG J, BUISMAN S C, WEERSING E, et al. CBX7 induces self-renewal of human normal and malignant hematopoietic stem and progenitor cells by canonical and non-canonical interactions[J]. Cell Rep, 2019, 26(7): 1906-1918.e8.
|
7 |
KLAUKE K, RADULOVIĆ V, BROEKHUIS M, et al. Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation[J]. Nat Cell Biol, 2013, 15(4): 353-362.
|
8 |
DEL GAUDIO N, DI COSTANZO A, LIU N Q, et al. CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway[J]. Mol Cancer, 2022, 21(1): 125.
|
9 |
HU F F, CHEN H, DUAN Y, et al. CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma[J]. Mol Ther Nucleic Acids, 2021, 27: 670-684.
|
10 |
WANG X, QIN G, LIANG X T, et al. Targeting the CK1α/CBX4 axis for metastasis in osteosarcoma[J]. Nat Commun, 2020, 11(1): 1141.
|
11 |
ZHANG C Z, CHEN S L, WANG C H, et al. CBX8 exhibits oncogenic activity via AKT/β-catenin activation in hepatocellular carcinoma[J]. Cancer Res, 2018, 78(1): 51-63.
|
12 |
MENG Q C, LI L, WANG L P. High CBX8 expression leads to poor prognosis in laryngeal squamous cell carcinoma by inducing EMT by activating the Wnt/β-catenin signaling pathway[J]. Front Oncol, 2022, 12: 881262.
|
13 |
DENG H L, GUAN X W, GONG L C, et al. CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer[J]. Sci Rep, 2019, 9(1): 197.
|
14 |
HUANG Z N, YAN Y L, ZHU Z, et al. CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10-ERK signaling[J]. Cell Death Dis, 2021, 12(6): 537.
|
15 |
BERNARD D, MARTINEZ-LEAL J F, RIZZO S, et al. CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus[J]. Oncogene, 2005, 24(36): 5543-5551.
|
16 |
FORZATI F, FEDERICO A, PALLANTE P, et al. CBX7 is a tumor suppressor in mice and humans[J]. J Clin Invest, 2012, 122(2): 612-623.
|
17 |
ZHANG Y, KANG M, ZHANG B, et al. m6A modification-mediated CBX8 induction regulates stemness and chemosensitivity of colon cancer via upregulation of LGR5[J]. Mol Cancer, 2019, 18(1): 185.
|
18 |
WANG G, TANG J J, ZHAN W X, et al. CBX8 suppresses tumor metastasis via repressing snail in esophageal squamous cell carcinoma[J]. Theranostics, 2017, 7(14): 3478-3488.
|
19 |
CONNELLY K E, WEAVER T M, ALPSOY A, et al. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association[J]. Nucleic Acids Res, 2019, 47(5): 2289-2305.
|
20 |
CERAMI E, GAO J J, DOGRUSOZ U, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data[J]. Cancer Discov, 2012, 2(5): 401-404.
|
21 |
SUBRAMANIAN A, TAMAYO P, MOOTHA V K, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles[J]. Proc Natl Acad Sci USA, 2005, 102(43): 15545-15550.
|
22 |
LIBERZON A, BIRGER C, THORVALDSDÓTTIR H, et al. The Molecular Signatures Database (MSigDB) hallmark gene set collection[J]. Cell Syst, 2015, 1(6): 417-425.
|
23 |
MAO L, CHEN J, LU X, et al. Proteomic analysis of lung cancer cells reveals a critical role of BCAT1 in cancer cell metastasis[J]. Theranostics, 2021, 11(19): 9705-9720.
|
24 |
XU M, LIU Q Q, JIA Y L, et al. BCAT1 promotes tumor cell migration and invasion in hepatocellular carcinoma[J]. Oncol Lett, 2016, 12(4): 2648-2656.
|
25 |
TANG J J, WANG G, ZHANG M F, et al. Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer[J]. Oncotarget, 2014, 5(21): 10778-10790.
|
26 |
SHANG S, YANG Y W, CHEN F, et al. TRIB3 reduces CD8+ T cell infiltration and induces immune evasion by repressing the STAT1-CXCL10 axis in colorectal cancer[J]. Sci Transl Med, 2022, 14(626): eabf0992.
|
27 |
JIANG Q, LI J, WANG J Y, et al. Inhibition of CDKL3 downregulates STAT1 thus suppressing prostate cancer development[J]. Cell Death Dis, 2023, 14(3): 189.
|
28 |
HATZIIEREMIA S, MOHAMMED Z, MCCALL P, et al. Loss of signal transducer and activator of transcription 1 is associated with prostate cancer recurrence[J]. Mol Carcinog, 2016, 55(11): 1667-1677.
|
29 |
KACHROO P, LEE M H, ZHANG L, et al. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer[J]. J Exp Clin Cancer Res, 2013, 32(1): 97.
|
30 |
LERCHENMÜLLER C, HEIßENBERG J, DAMILANO F, et al. S100A6 regulates endothelial cell cycle progression by attenuating antiproliferative signal transducers and activators of transcription 1 signaling[J]. Arterioscler Thromb Vasc Biol, 2016, 36(9): 1854-1867.
|
31 |
WANG T, HAN S L, DU G. S100A6 represses Calu-6 lung cancer cells growth via inhibiting cell proliferation, migration, invasion and enhancing apoptosis[J]. Cell Biochem Funct, 2021, 39(6): 771-779.
|
32 |
MOUSSA H F, BSTEH D, YELAGANDULA R, et al. Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing[J]. Nat Commun, 2019, 10(1): 1931.
|
33 |
MACRAE T A, FOTHERGILL-ROBINSON J, RAMALHO-SANTOS M. Regulation, functions and transmission of bivalent chromatin during mammalian development[J]. Nat Rev Mol Cell Biol, 2023, 24(1): 6-26.
|
34 |
TERRANOVA C J, TANG M, MAITITUOHETI M, et al. Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy[J]. Cell Rep, 2021, 36(3): 109410.
|
35 |
CHAN H L, BECKEDORFF F, ZHANG Y S, et al. Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms[J]. Nat Commun, 2018, 9(1): 3377.
|
36 |
CHUNG C Y, SUN Z, MULLOKANDOV G, et al. Cbx8 acts non-canonically with Wdr5 to promote mammary tumorigenesis[J]. Cell Rep, 2016, 16(2): 472-486.
|