上海交通大学学报（医学版）

上海交通大学学报（医学版）

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儿童大环内酯类耐药肺炎支原体感染研究进展

王兰1，吴良霞2   

  1. 1.上海市普陀区中心医院儿科， 上海 200062； 2.上海交通大学附属第六人民医院儿科， 上海 200233
  • 出版日期:2015-05-28 发布日期:2015-06-04
  • 作者简介:王兰（1981—）， 女， 主治医师， 硕士生; 电子信箱: wangnan1815@163.com。

Advances of macrolide resistant Mycoplasma pneumoniae infection of children

WANG Lan1, WU Liang-xia2   

  1. 1.Department of Paediatrics, Shanghai Putuo District Central Hospital, Shanghai 200062, China; 2.Department of Paediatrics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • Online:2015-05-28 Published:2015-06-04

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摘要：

肺炎支原体是儿童呼吸道感染的重要病原之一。儿童肺炎支原体感染的治疗通常使用大环内酯类抗生素。2001年以来，世界各地尤其是东亚地区对大环内酯类耐药肺炎支原体的报道日益增多。该文就肺炎支原体耐药株感染的现状、耐药机制及耐药株感染患儿的临床特征进行综述，讨论针对此种情况最合理的处理方案。

关键词: 儿童, 大环内酯类, 耐药, 肺炎支原体

Abstract:

Mycoplasma pneumoniae is one of major pathogens causing respiratory tract infection of children and is usually treated with macrolides. Since 2001, reported macrolide resistant isolates of Mycoplasma pneumoniae has increased worldwide, especially in East Asia. This paper reviews the current situation and mechanisms of macrolide resistance of Mycoplasma pneumoniae and clinical characteristics of pediatric patients infected by macrolide resistant Mycoplasma pneumoniae, and discusses the best approach to deal with this situation.

Key words: children, macrolides, macrolide-resistant, Mycoplasma pneumoniae