上海交通大学学报(医学版)

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冠状动脉与髂动脉粥样硬化病变的相关性研究

华沙,赵建荣,邱筱炜   

  1. 上海交通大学  医学院附属瑞金医院卢湾分院心血管科, 上海 200020
  • 出版日期:2016-02-28 发布日期:2016-03-29
  • 通讯作者: 赵建荣, 电子信箱: drzjr@126.com。
  • 作者简介:华沙(1985—), 女, 主治医师, 硕士; 电子信箱: 699146@qq.com。

Correlation between coronary and iliac atherosclerosis

HUA Sha, ZHAO Jian-rong, QIU Xiao-wei   

  1. Department of Cardiovascular Diseases, Luwan Branch of Ruijin Hospital,Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China
  • Online:2016-02-28 Published:2016-03-29

摘要:

目的 在冠状动脉造影的同时行髂动脉造影,研究冠状动脉与髂动脉粥样硬化病变的相关性。方法 共纳入288例在冠状动脉造影后即刻行髂动脉造影的患者,分析髂动脉粥样硬化病变的检出率、危险因素及其与冠状动脉粥样硬化病变及其严重程度的相关性。结果 入选患者平均年龄为(66.64±10.58)岁,髂动脉粥样硬化病变的总检出率为42.7%(123/288);冠状动脉粥样硬化性心脏病(冠心病)患者中髂动脉粥样硬化病变的发生率(54.8%)明显高于非冠心病患者(23.4%)(P=0.000)。危险因素分析结果显示:男性、高龄、高血压病、糖尿病、吸烟、高胆固醇血症为髂动脉病变的危险因素。髂动脉病变与冠状动脉病变及其严重程度(病变支数)显著相关(P值分别为0.001和0.000)。结论 髂动脉粥样硬化病变与冠心病具有共同危险因素,且髂动脉病变与冠状动脉病变的严重程度相关。

关键词: 动脉粥样硬化, 髂动脉, 冠状动脉粥样硬化性心脏病, 冠状动脉造影术

Abstract:

Objective To explore the correlation between the coronary and iliac artery atherosclerosis by simultaneously conducting iliac angiography and coronary angiography (CAG). Methods A total of 288 patients who underwent iliac angiography immediately after coronary angiography were enrolled. The detection rate and risk factors of iliac atherosclerosis and their correlation with coronary atherosclerosis and its severity were analyzed. Results The mean age of the patients was (66.64±10.58) years. The total detection rate of iliac atherosclerosis was 42.7% (123/288). The incidence of iliac atherosclerosis of patients with coronary atherosclerosis was 54.8%, which was significantly higher than that (23.4%) of patients without coronary atherosclerosis (P=0.000). The result of risk factor analysis showed that elder, male, smoking, hypertension, diabetes mellitus, and hypercholesterolemia were risk factors of iliac atherosclerosis. The iliac atherosclerosis significant correlated with coronary atherosclerosis and its severity (the number of involved vessels) (P=0.001 and 0.000). Conclusion Risk factors of iliac atherosclerosis are similar to those of coronary atherosclerosis and iliac atherosclerosis also correlates with the severity of coronary atherosclerosis.

Key words: atherosclerosis, iliac artery, coronary artery disease, coronary angiography