上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2020, Vol. 40 ›› Issue (4): 489-.doi: 10.3969/j.issn.1674-8115.2020.04.012

• 论著·临床研究 • 上一篇    下一篇

不同程度小于胎龄儿的母体临床危险因素分析

胡绪林*，陈 妍*，夏红萍，张拥军   

  1. 上海交通大学医学院附属新华医院新生儿科，上海 200092
  • 出版日期:2020-04-28 发布日期:2020-05-22
  • 通讯作者: 张拥军，电子信箱：zhangyongjun@sjtu.edu.cn。
  • 作者简介:胡绪林（1985—），男，主治医师，硕士；电子信箱：huxulin52000@163.com；陈 妍（1969—），女，主任医师，博士；电子信箱：chenyan783563@163.com。*为共同第一作者。
  • 基金资助:
    上海市卫生与计划生育委员会科研课题（201740195）。

Analysis of maternal clinical risk factors for different degrees of small for gestational age infant

HU Xu-lin, CHEN Yan, XIA Hong-ping, ZHANG Yong-jun   

  1. Department of Neonatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
  • Online:2020-04-28 Published:2020-05-22
  • Supported by:
    Shanghai Municipal Health and Family Planning Commission Foundation ( 201740195).

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摘要： 目的·探讨不同程度小于胎龄儿（small for gestational age infant, SGA）母体的孕前及孕期高危因素。方法·纳入2013年9月—2016年12月在上海交通大学医学院附属新华医院分娩的母体及单胎新生儿，根据子代不同出生体质量所在百分位分为4组：轻度SGA组（SGA5th～10th）、中度SGA组（SGA3rd～5th）、重度SGA组（rd）、正常对照组。采用多变量Logistic回归分析SGA母体孕期及孕前高危因素与不同程度SGA发生的相关性。结果·母体的年龄、产次、受教育程度、早产发生率、胎儿性别与SGA无相关性。母体体质量指数（body mass index，BMI）、妊娠高血压和接受辅助生殖与SGA显著相关（均P结论·母体低BMI、妊娠高血压是中度SGA的高危因素，接受辅助生殖是重度SGA的高危因素；不同程度SGA的高危因素并不相同。

关键词: 小于胎龄儿, 母体, 体质量指数, 妊娠高血压, 辅助生殖

Abstract:

Objective · To explore the pregestational and gestational risk factors associated with small for gestational age infant (SGA)different degrees. Methods · Mothers and single newborns delivered at Xinhua Hospital, Shanghai Jiao Tong University School of Medicine September 2013 to December 2016 were included. Multivariate Logistic regression was used to analyze the correlation between maternal pregnancy and pre-pregnancy risk factors and the occurrence of SGAdifferent degrees. Results · There were no statistically significant differences in maternal age, number of birth, education level, incidence of preterm birth and fetal sex in SGA. Maternal body mass index (BMI), gestational hypertension and accepting assisted reproduction were significantly correlated with SGA (all PConclusion · Maternal low BMI and hypertension are the risk factors of moderate SGA and accepting assisted reproduction are the risk factors of severe SGA, and the risk factors of SGAdifferent degrees are not the same.

Key words: small for gestational age infant (SGA), mother, body mass index (BMI), gestational hypertension, assisted reproduction