上海交通大学学报（医学版）

›› 2009, Vol. 29 ›› Issue (8): 990-.

• 综述 • 上一篇    下一篇

肝细胞球形聚集体培养研究进展

匡 洁, 韩宝三 综述；彭承宏, 沈柏用 审校   

  1. 上海交通大学 医学院瑞金医院外科,  器官移植中心, 消化外科研究所, 上海 200025
  • 出版日期:2009-08-25 发布日期:2009-09-27
  • 作者简介:匡洁（1975—）, 女, 主治医师, 学士；电子信箱: yuwenlon@sina.com。
  • 基金资助:

    国家高技术研究发展计划(“863”计划)（2007AA02Z487）, 国家自然科学基金(30672043, 30772105), 上海市科委自然科学基金(07ZR14076)

Research progress of spheroid colonies culture of liver cells

KUANG Jie, HAN Bao-san reviewer；PENG Cheng-hong, SHEN Bai-yong reviser   

  1. Department of Surgery, Center of Organ Transplantation, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2009-08-25 Published:2009-09-27
  • Supported by:

    National High Technology Research and Development Program of China, 863 program, 2007AA02Z487；National Natural Science Foundation of China, 30672043, 30772105；Shanghai Science and Technology Foundation, 07ZR14076

PDF (PC)

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摘要：

生物人工肝在治疗肝功能衰竭中起重要作用。球形聚集体培养作为肝细胞培养的主要方式之一，旨在达到高密度、维持长时间生物活性的目标。文章就近年来肝细胞球形聚集体培养的影响因素和培养方式作一综述。

关键词: 生物人工肝, 肝细胞, 球形聚集体培养

Abstract:

Bioartificial liver plays an important role in the treatment of liver failure. Spheroid colonies culture is one of the main methods in culturing liver cells to maintain high density and biofunction for a long time. This paper reviews the influential factors and methods for spheroid colonies culture of liver cells.

Key words: bioartificial liver, hepatocyte, spheroid colony culture

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