Review of the factors influencing bone metabolism in schizophrenia

doi:10.3969/j.issn.1674-8115.2021.07.021

Abstract

Abstract:

The patients with schizophrenia experience a higher rate of low bone mineral density, osteoporosis and fractures than the general population, which affects not only their quality of life but also their long-term outcomes. Previous studies have shown that there are many factors affecting individual bone metabolism, including drugs, gender, age, hypogonadism, lifestyle, etc. Combined with clinical research, this article summarizes three aspects, i.e.,the disease itself, the use of antipsychotics and the unhealthy lifestyle. This review aims to discuss the influencing factors of bone metabolism in the patients with schizophrenia, and then expound briefly on the diagnosis and intervention measures of osteoporosis, which may provide a reference for clinical prevention and intervention of osteoporosis in the patients with schizophrenia.

Key words: schizophrenia, osteoporosis, bone metabolism, antipsychotics

CLC Number:

R749.3

Hong-yan XUAN, Li-hua WANG, Hua-fang LI. Review of the factors influencing bone metabolism in schizophrenia[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(7): 972-976.

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