Progress of transcranial direct current stimulation in the treatment of children and adolescents psychiatric disorders

doi:10.3969/j.issn.1674-8115.2021.10.015

Abstract

Abstract:

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique. It can modulate brain current activities and treat psychiatric disorder through affecting neural excitability and synaptic plasticity. At present, there are substantial application researches of tDCS, and it is effective on the treatment of adult depressive disorder, bipolar depressive disorder, schizophrenia and other mental diseases. Preliminary researches have showed that children and adolescents have certain tolerance to tDCS, however, there are only few randomized controlled clinical studies about tDCS applying to the children and adolescents with psychiatric disorders, and reliable conclusions couldn't be drawn due to limitations of small sample size and open label trials. This paper reviews the utilization of tDCS among children and adolescents with schizophrenia, attention deficit/hyperactivity disorder, autism spectrum disorder and dyslexia. Details including parameters, efficacy, side effects and limitations are discussed, and different sessions, duration, current, intensity, stimulation sites and effect are compared. Information discussed may provide reference for development of neuromodulation techniques and clinical applications of tDCS to the treatment of children and adolescents with psychiatric disorders.

Key words: transcranial direct current stimulation (tDCS), child, adolescent, psychiatric disorder, schizophrenia, attention deficit/hyperactivity disorder, autism spectrum disorder, dyslexia

CLC Number:

R749

Nuo-shi QIAN, Wu HONG, Chun-bo LI. Progress of transcranial direct current stimulation in the treatment of children and adolescents psychiatric disorders[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(10): 1366-1370.

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