Journal of Shanghai Jiao Tong University (Medical Science) ›› 2025, Vol. 45 ›› Issue (9): 1249-1255.doi: 10.3969/j.issn.1674-8115.2025.09.017

• Review • Previous Articles     Next Articles

Research progress on intelligent diagnosis of eye diseases based on facial photos

XU Hanwen1,2, CHEN Moxin1,2, LIANG Xiaoyi1,2, SHU Qin1,2, NIE Wanqin1,2, YANG Xuefeng1,2, SHEN Minxuan1,2, LI Xiaojing1,2, CAO Yu3, LI Lin1,2()   

  1. 1.Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
    2.Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai 200011, China
    3.Shanghai Institute of Precision Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China
  • Received:2025-05-05 Accepted:2025-06-25 Online:2025-09-28 Published:2025-09-30
  • Contact: LI Lin E-mail:lin_li@sjtu.edu.cn
  • Supported by:
    Shanghai Health Commission Research Special Fund for the Health Industry(20244Z0005);“Two-hundred Talents” Program of Shanghai Jiao Tong University School of Medicine(20172018)

Abstract:

The number of patients with eye diseases in China is enormous, and the negative effects of these conditions, such as impaired visual function, psychological burdens, and restricted social participation, are becoming increasingly severe. Due to the limited and unevenly distributed ophthalmic resources, and the significant limitations of traditional diagnostic and therapeutic approaches in terms of accuracy and efficiency, there is an urgent need for more sensitive and efficient modalities. With the rapid advancement of artificial intelligence technology, ophthalmic diagnosis has entered a new stage of intelligent transformation. Facial photos, as a noninvasive and convenient medium, show unique advantages in eye disease diagnosis. Artificial intelligence systems based on facial photo analysis have been applied to the screening and diagnosis of conditions such as myopia, strabismus, ptosis, and thyroid eye disease, showing promising results. This review introduces the workflow of intelligent diagnosis for ocular diseases based on facial photographs, with a focus on recapitulating relevant research findings both domestically and internationally in recent years. It summarizes the innovative features and application advantages of intelligent diagnosis systems for eye diseases based on facial photos, analyzes the current technical bottlenecks and challenges in application, proposes corresponding countermeasures, and discusses future development directions, aiming to provide references and new insights for the intelligent screening and diagnosis of eye diseases.

Key words: eye disease, artificial intelligence, diagnosis, face, photo

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