ACE2/Apelin signaling and atherosclerosis

doi:10.3969/j.issn.1674-8115.2016.06.026

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ACE2/Apelin signaling and atherosclerosis

ZHANG Zhen-zhou, SONG Bei, ZHONG Jiu-chang

State Key Laboratory of Medical Genomics, Ruijin Hospital， Shanghai Jiao Tong University School of Medicine， Shanghai Institute of Hypertension， Shanghai 200025, China

Online:2016-06-28 Published:2016-07-25
Supported by:
National Major Research Plan Training Program， 91339108; National Basic Research Program of China， 2014CB542300; National Natural Science Foundation of China， 81370362， 81170246; Scientific Research Project of Health Bureau of Shanghai， 201440368

Abstract

Abstract:

Atherosclerotic diseases have become the leading cause of human death. The renin-angiotensin system is an important factor for promoting the occurrence and development of atherosclerotic cardiovascular diseases. Studies have revealed that the ACE2/Apelin signaling plays a protective role in the cardiovascular system. This article reviews the latest research advances in ACE2/Apelin signaling and its regulatory role in atherosclerosis.

Key words: atherosclerosis, renin-angiotensin system, angiotensin-converting enzyme 2, Apelin

ZHANG Zhen-zhou, SONG Bei, ZHONG Jiu-chang. ACE2/Apelin signaling and atherosclerosis[J]. , doi: 10.3969/j.issn.1674-8115.2016.06.026.

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ACE2/Apelin signaling and atherosclerosis

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