›› 2011, Vol. 31 ›› Issue (8): 1096-.doi: 10.3969/j.issn.1674-8115.2011.08.010

• Monographic report (Ophthalmology and Visual Sciences) • Previous Articles     Next Articles

Relationship between myopia and eyeball and systemic immune inflammation

ZHOU Ji-bo1,2, QU Jia1   

  1. 1.Optical Research Center of the Ministry of Health of China, Wenzhou 325027, China；2.Department of Ophthalmology, the Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China
  • Online:2011-08-28 Published:2011-08-29
  • Supported by:

    Shanghai Leading Academic Discipline Project, S30205；Shanghai Jiaotong University School of Medicine Foundation, YZ1022

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Abstract:

Inflammation is one of the basic pathophysiological processes of human beings, and inflammation involving sclera often results in myopia. Inflammation may derive from the other tissues and organs, or from sclera, choroid, retina and surrounding tissues. The possible pathogenesis may be that sclera thinning is caused by the release of inflammation factors, and myopia is developed by the lengthening of vitreous chamber of ocular globe. To interpret the relationship between myopia and inflammation may accomplish the etiology of myopia, enhance the understanding of pathogenesis of myopia, and help to diagnose and treat the disease properly.

Key words: myopia, inflammation, sclera, matrix metalloproteinase-2