上海交通大学学报(医学版) ›› 2015, Vol. 35 ›› Issue (10): 1565-.doi: 10.3969/j.issn.1674-8115.2015.10.027

• 综述 • 上一篇    下一篇

磁共振波谱技术对γ-氨基丁酸在精神疾病中的研究进展

张宗凤,范青,王媛,张海音,王振,肖泽萍   

  1. 上海交通大学 医学院附属精神卫生中心, 上海市精神疾病临床医学中心, 上海200030
  • 出版日期:2015-10-20 发布日期:2015-12-22
  • 通讯作者: 肖泽萍, 电子信箱: xiaozeping88@163.com
  • 作者简介:张宗凤(1990—), 女, 硕士生; 电子信箱: zzf19900713@163.com
  • 基金资助:

     国家自然科学基金 (81171280,81301153);国家临床重点专科-上海市精神卫生中心(卫生部医政司2011-873);上海市精神卫生中心重点特色专科(2013-YJTSZK-02)

Advances of γ-aminobutyric acid of patients with mental disorders by magnetic resonance spectroscopy technology

ZHANG Zong-feng, FAN Qing, WANG Yuan, ZHANG Hai-yin, WANG Zhen, XIAO Ze-ping   

  1. Shanghai Mental Health Center, Shanghai Clinical Center for Mental Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai200030, China
  • Online:2015-10-20 Published:2015-12-22
  • Supported by:

    National Natural Science Foundation of China, 81171280, 81301153; National Key Clinical Disciplines at Shanghai Mental Health Center, OMA-MH 2011-873; The Key Characteristic Specialist Department of Shanghai Mental Health Center, 2013-YJTSZK-02

摘要:

脑内γ-氨基丁酸能神经元功能的异常见于多种精神疾病,如焦虑障碍、心境障碍、睡眠障碍、精神分裂症、孤独症谱系障碍及强迫症等。利用磁共振波谱技术研究γ-氨基丁酸在精神疾病中的作用取得了一定进展,该文对此进行综述。

关键词: &gamma, -氨基丁酸, 磁共振波谱技术, 精神疾病

Abstract:

The abnormalities of functions of γ-aminobutyric acid neurons in the brain are found in a variety of mental disorders, such as anxiety disorder, mood disorder, sleep disorder, schizophrenia, autism spectrum disorder, and obsessive-compulsive disorder, etc. This paper reviews advances in studies on the effects of γ-aminobutyric acid on mental disorders by the magnetic resonance spectroscopy technology.

Key words: γ-aminobutyric acid, magnetic resonance spectroscopy technology, mental disorders