上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2018, Vol. 38 ›› Issue (8): 954-.doi: 10.3969/j.issn.1674-8115.2018.08.016

• 综述 • 上一篇    下一篇

PET/CT不同判读方法对霍奇金淋巴瘤及弥漫大 B细胞淋巴瘤的预后评估作用

谢微 1，江旭峰 2，赵维莅 1，王黎 1   

  1. 1. 上海交通大学医学院附属瑞金医院血液科，上海血液学研究所，医学基因组学国家重点实验室，上海 200025；2. 上海交通大学医学院附属瑞金医院核医学科，上海 200025
  • 出版日期:2018-08-28 发布日期:2018-09-11
  • 作者简介:谢微（1994—），女，硕士生；电子信箱： xieweimed1994@outlook.com。
  • 基金资助:
    国家自然科学基金（ 81325003，81520108003，81670716）；上海市科学技术委员会项目（ 14430723400，14140903100，16JC1405800）；上海市杰出青年医学人才培养资助计划；上海交通大学 SMC-晨星青年学者奖励计划；上海市教育委员会高峰高原学科建设计划（ 20152206，20152208）

Prognostic evaluation of different PET/CT reading methods in Hodgkin lymphoma and diffused large B-cell lymphoma

XIE Wei1, JIANG Xu-feng2, ZHAO Wei-li1, WANG Li1   

  1. 1. State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Department of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2. Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Online:2018-08-28 Published:2018-09-11
  • Supported by:
    National Natural Science Foundation of China, 81325003, 81520108003, 81670716; Project of Science and Technology Commission of Shanghai Municipality, 14430723400, 14140903100, 16JC1405800; Shanghai Outstanding Youth Medical Talents Training Funding Program; Shanghai Jiao Tong University SMC-Morning Star Young Scholars; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Support, 20152206, 20152208

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摘要： 氟代脱氧葡萄糖正电子发射体摄影技术 -计算机体层摄影技术（ 18F-fluoro-deoxyglucose positron emission tomography-computed tomography， 18F-FDG PET/CT，简称 PET/CT）已成为淋巴瘤分期及预后评估的重要影像学方法。因淋巴瘤各亚型的生物学特性、治疗反应和预后差异较大，该文主要对 PET/CT在霍奇金淋巴瘤（Hodgkin lymphoma，HL）、弥漫大 B细胞淋巴瘤（diffused large B-cell lymphoma，DLBCL）中的预后评估进展进行综述，阐述了治疗中期 PET/CT在 HL预后评估中的积极意义，以及在 DLBCL预后评估作用中存在的争议，并论述了半定量法在未来应用的前景。

关键词: 氟代脱氧葡萄糖正电子发射体摄影技术 -计算机体层摄影技术, 淋巴瘤, 霍奇金淋巴瘤, 弥漫大 B细胞淋巴瘤, 预后评估, 半定量法

Abstract:

18F-fluoro-deoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) has been used as a crucial imaging modality for staging and prognosis evaluation in the patients with lymphoma. Since biological characteristics, treatment responses and prognosis vary in different subtypes of lymphoma, this review mainly focused on progress of 18F-FDG PET/CTevaluationin prognosis of Hodgkin lymphoma (HL)and diffused large B-cell lymphoma (DLBCL). The significance in prognostic evaluation of interim 18F-FDG PET/CT in HL is well-known, but it still remains controversy in DLBCL. Moreover, the semi-quantitative method of 18F-FDG PET/CT evaluation in lymphoma has bright future.

Key words: 18F-fluoro-deoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT), lymphoma, Hodgkin lymphoma (HL), diffusedlarge B-cell lymphoma (DLBCL), prognostic evaluation, semi-quantitative method

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