上海交通大学学报（医学版）

›› 2009, Vol. 29 ›› Issue (9): 1116-.

• 综述 • 上一篇    下一篇

趋化因子及其受体在妊娠免疫耐受中的作用

肖世金 综述, 赵爱民 审校   

  1. 上海交通大学 医学院仁济医院妇产科, 上海 200001
  • 出版日期:2009-09-25 发布日期:2009-09-29
  • 作者简介:肖世金（1983—）, 男, 硕士生；电子信箱: shjxiao@sina.com。
  • 基金资助:

    上海市自然科学基金(072R14072)

Effects of chemokines and their receptors in pregnancy immune tolerance

XIAO Shi-jin reviewer, ZHAO Ai-min reviser   

  1. Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200001, China
  • Online:2009-09-25 Published:2009-09-29
  • Supported by:

    Shanghai Natural Science Foundation, 072R14072

PDF (PC)

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摘要：

妊娠免疫耐受是正常妊娠时母体形成的一种特殊类型的外周免疫耐受，保护作为半同种移植物的胎儿不被母体免疫系统排斥而成功妊娠。趋化因子及其受体参与免疫细胞的活化和游走等过程，在诱导免疫耐受中发挥重要作用。文章就趋化因子及其受体在妊娠免疫耐受中的作用进行了综述。

关键词: 妊娠, 免疫耐受, 趋化因子, 趋化因子受体

Abstract:

Pregnancy immune tolerance is a special type of peripheral immunological tolerance formed by maternal immune system during pregnancy, which urges maternal immune system not to reject fetus as half-allogeneic graft. Chemokines and their receptors play important roles in induced immune tolerance as participating in activation and migration of immunocytes. This article reviews the effects of chemokines and their receptors in pregnancy immune tolerance.

Key words: pregnancy, immune tolerance, chemokine, chemokine receptor

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