上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (2): 238-.doi: 10.3969/j.issn.1674-8115.2011.02.027

• 综述 • 上一篇    下一篇

神经干细胞在治疗脑缺血性疾病中的应用

周秋梦, 仲 骏   

  1. 上海交通大学 医学院附属新华医院神经外科, 上海 200092
  • 出版日期:2011-02-28 发布日期:2011-03-01
  • 通讯作者: 仲 骏, 电子信箱: zhongMDphD@sjtu.edu.cn。
  • 作者简介:周秋梦（1986—）, 女, 硕士生；电子信箱: fairy1551@hotmail.com。

Value of neural stem cells in treatment of cerebral ischemic diseases

ZHOU Qiu-meng, ZHONG Jun   

  1. Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Online:2011-02-28 Published:2011-03-01

PDF (PC)

2012

摘要：

由于中枢神经系统对于缺血、缺氧等外界因素十分敏感，脑缺血性疾病的治疗一直是临床上的难题。大量研究表明，神经干细胞在中枢神经系统损伤后有再生和分化的潜能，脑组织神经元可能并不属于终末分化细胞，这为临床治疗脑缺血性疾病带来希望。文章就神经干细胞在治疗脑缺血性疾病中的应用作一综述。

关键词: 神经干细胞, 脑缺血, 生长因子, 脊髓电刺激, 脑血流量

Abstract:

Because the central nerve system is susceptible to ischemia and hypoxia, the treatment of cerebral ischemic diseases has been regarded as a hard task. Nowadays, numerous studies have demonstrated that neural stem cells have potential capability of proliferation and differentiation following injury. Accordingly, cerebral neurons might not be the terminally differentiated cells, which may bring a new therapy to the cerebral ischemic diseases. The value of neural stem cells in the treatment of cerebral ischemic diseases is reviewed in this paper.

Key words: neural stem cell, cerebral ischemia, growth factor, spinal cord simulation, cerebral blood flow