上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (7): 1031-.doi: 10.3969/j.issn.1674-8115.2011.07.036

• 综述 • 上一篇    下一篇

人体细胞核移植研究进展

关小红, 冯 云   

  1. 上海交通大学 医学院附属瑞金医院生殖医学中心, 上海 200025
  • 出版日期:2011-07-28 发布日期:2011-07-27
  • 通讯作者: 冯 云, 电子信箱: artruijin@yahoo.com.cn。
  • 作者简介:关小红（1985—）, 女, 硕士生；电子信箱: guanhong816@163.com。
  • 基金资助:

    国家高技术研究发展计划（“863”计划）（20060102A1022）

Research progress of human somatic cell nuclear transfer

GUAN Xiao-hong, FENG Yun   

  1. Reproductive Medical Center, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2011-07-28 Published:2011-07-27
  • Supported by:

    National High-tech Research and Development Program of China, “863” Project, 20060102A1022

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摘要：

为解决免疫排斥问题，核移植技术获得深入发展。动物核移植技术方面的成功开展，加之再生医学与药物治疗的需要，促进了对人特异性胚胎干细胞的研究。文章对人体细胞核移植的研究进展及种间核移植研究存在问题和面临的挑战作一综述。

关键词: 人体细胞核移植, 种间核移植, 胚胎干细胞

Abstract:

To solve the problem of immune incompatibility, nuclear transfer has been deeply developed. The successful development of animal nuclear transfer and the requirements from regenerative medicine and drug therapy promote the research of human specific embryonic stem cells. This review discusses the research progress of human somatic cell nuclear transfer and obstacles and challenges of interspecies nuclear transfer.

Key words: human somatic cell nuclear transfer, interspecies nuclear transfer, embryonic stem cell