›› 2013, Vol. 33 ›› Issue (1): 109-.doi: 10.3969/j.issn.1674-8115.2013.01.022

• 综述 • 上一篇    下一篇


黄佳卉1, 汪 泱1,2, 王共先1   

  1. 1.南昌大学 第一附属医院泌尿外科研究所, 南昌 330006; 2.上海交通大学创伤骨科研究所, 上海 200233
  • 出版日期:2013-01-28 发布日期:2013-02-06
  • 通讯作者: 汪 泱, 电子信箱: wangy63cn@126.com。
  • 作者简介:黄佳卉(1984—), 女, 硕士生;电子信箱: jiahuihuang33006@163.com。
  • 基金资助:

    国家自然科学基金(81170640, 30960385)

Research progress of pluripotent stem cells and kidney regeneration

HUANG Jia-hui1, WANG Yang1,2, WANG Gong-xian1   

  1. 1.Institute of Urology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China; 2.Institute of Orthopaedic Trauma, Shanghai Jiaotong University, Shanghai 200233, China
  • Online:2013-01-28 Published:2013-02-06
  • Supported by:

    National Natural Science Foundation of China, 81170640, 30960385



关键词: 多能干细胞, 胚胎干细胞, 诱导性多能干细胞, 肾脏再生, 细胞分化


Although renal transplantation has been proved to be an effective therapeutic strategy for most patients with end-stage renal failure, it is associated with some limitations, including the shortage of donor organs, immune rejection and a lifelong immunosuppressive regimen. Pluripotent stem cells, especially embryonic stem cells and induced pluripotent stem cells, can differentiate into any cell types in the body and show a good prospect of application on tissue and organ regeneration. The research progress of pluripotent stem cells and kidney regeneration is reviewed in this paper.

Key words: pluripotent stem cell, embryonic stem cell, induced pluripotent stem cell, kidney regeneration, cell differentiation