›› 2011, Vol. 31 ›› Issue (6): 848-.doi: 10.3969/j.issn.1674-8115.2011.06.038

• Review • Previous Articles     Next Articles

Impact of oncolytic viruses in combination with radiotherapy on tumor cells

YAO Yu-ting1,2, QIAN Guan-xiang2, GE Sheng-fang1,2   

  1. 1.Department of Ophthalmology, the Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China；2.Department of Biochemistry and Molecular Biology, Basic Medical College, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2011-06-28 Published:2011-06-27
  • Supported by:

    National Natural Science Foundation of China, 10979034；Shanghai Key Discipline Foundation, S30205

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Abstract:

Oncolytic viruses have been developed as a new approach for the treatment of cancer. Oncolytic viruses in combination with radiotherapy may have an important impact for the treatment of metastatic cancer after the approval of oncolytic adenovirus for clinical tumor treatment. In this review, the killing effects on tumor cells of oncolytic viruses in combination with radiotherapy are discussed.

Key words: oncolytic virus, radiotherapy, tumor, gene therapy