Abstract: Atypical antipsychotic drugs have overcome the serious prolactin elevation and extrapyramidal symptoms of typical antipsychotic drugs, and become the first-line treatment for psychiatry. Studies have found that atypical antipsychotic drugs can modulate the immune inflammatory state of patients and affect their cognitive function, and there is increasing evidence suggesting that neuroimmune disorders may impair cognitive function in schizophrenia. This article reviews the progress of neuroimmune mechanisms of cognitive function in schizophrenia and the effect of atypical antipsychotic drugs on it.

Key words: antipsychotics, cognitive function, schizophrenia, neuroimmune