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Preliminary study on application of visual P300 potentials in responsible appreciation of schizophrenia patients by judicial expertise

HAN Hui-qin1, XIE Bin1, MU Jun-lin2, YANG Xiao-min1, ZHANG Ming-dao1, LOU Fei-ying1, LIANG Jian-hua1, CHEN Chong1   

  1. 1．Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China； 2．Henan Provincial Mental Hospital, Zhengzhou 453002, China
  • Online:2014-01-28 Published:2014-01-29
  • Supported by:

    Foundation of Shanghai Mental Health Center, 2011-YJ-09; Major Science and Technology Support Program of Ministry of Science and Technology in the National “12th 5-year Plan” of China, 2012BAK16B04; Young Scientists Project of National Natural Science Foundation of China, 81202388

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Abstract:

Objective To explore the value of visual P300 potentials in responsible appreciation of schizophrenia patients by judicial expertise. Methods Sixty-eight schizophrenia patients without responsible ability (group A) and 59 schizophrenia patients with limited responsible ability (group B) by judicial expertise and 58 healthy volunteers (group C) were enrolled in this study. They were given visual P300 potentials test. Results Compared to group C, latent periods of N1, N2, and P3 of P300 in groups A and B were significantly longer (P<0.01), and the amplitude of P3 decreased markedly (P<0.01). Compared to group B, latent periods of N1, N2, and P3 of P300 in group A were significantly longer, and amplitude of P3 decreased markedly (P<0.01). Conclusion Visual P300 potentials test has referential meaning in responsible appreciation of schizophrenia by judicial expertise, which needs confirmation by long follow-up.

Key words: judicial expertise, responsible ability, schizophrenia, visual P300 potentials