›› 2010, Vol. 30 ›› Issue (12): 1550-.doi: 10.3969/j.issn.1674-8115.2010.12.024

• Review • Previous Articles     Next Articles

Relationship between microRNA-155 and malignant tumors

SHI Lin-jun, ZHOU Zeng-tong, JIANG Wei-wen   

  1. Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China
  • Online:2010-12-25 Published:2010-12-31
  • Supported by:

    National Natural Science Foundation of China, 30872887；Shanghai Science and Technology Committee Foundation, 08DZ2271100；Shanghai Key Discipline Construction Project, S30206

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Abstract:

MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally modulate the expression of multiple target genes and are thus implicated in a wide array of cellular and developmental processes. Recently miRNAs and their close associations with malignant tumors remain a major concern. Nowadays microRNA-155(miRNA-155) has been found to be involved in different types of malignant tumors. Here we summarize the research progress of relationship between miRNA-155 and its association with malignant tumors.

Key words: microRNA, microRNA-155, malignant tumor, target gene