上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (11): 1385-.doi: 10.3969/j.issn.1674-8115.2010.11.016

• 论著（临床研究） • 上一篇    下一篇

后循环梗死患者的危险因素及预后分析

郭义坤, 施国文, 李焰生   

  1. 上海交通大学 医学院附属仁济医院神经内科, 上海 200127
  • 出版日期:2010-11-25 发布日期:2010-11-29
  • 通讯作者: 李焰生, 电子信箱: liyans@hotmail.com。
  • 作者简介:郭义坤（1982—）, 男, 硕士生；电子信箱: Guoyikun000@163.com。

Analysis of risk factors and prognosis in patients with posterior circulation ischemic stroke

GUO Yi-kun, SHI Guo-wen, LI Yan-sheng   

  1. Department of Neurology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2010-11-25 Published:2010-11-29

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摘要：

目的 研究后循环脑梗死（PCS）患者的危险因素分布特点及其对预后的影响。方法 收集129例经临床及影像学检查证实的PCS患者的人口学、入院NIHSS评分、血管危险因素等资料，随访3个月以了解患者预后，统计危险因素的发生情况并分析其与预后的关系。结果 在所调查的危险因素中，常见的依次为高血压（83.7%）、高脂血症（56.6%）、吸烟（39.5%）及高血糖（39.5%）。有0～7个危险因素的患者分别占4.65%、10.85%、23.26%、27.13%、24.81%、4.65%、3.88%和0.78%。多数患者在高血压的基础上合并其他危险因素。入院NIHSS评分与3个月预后独立相关（OR=1.58，95%CI 1.28～1.96），而各血管危险因素均不与患者的预后独立相关。结论 前后循环梗死患者的危险因素并无实质差异，对PCS患者进行干预时应注重对这些危险因素的干预。危险因素影响PCS的发生但不能决定患者的预后，不能仅依据危险因素判断患者的预后。

关键词: 脑梗死, 后循环, 危险因素, 预后

Abstract:

Objective To investigate the distribution of risk factors and its influence on prognosis in patients with posterior circulation ischemic stroke (PCS). Methods The data of demographics, NIHSS scores on admission and vascular risk factors were collected from 129 patients with PCS confirmed by clinical and imaging examinations. Patients were followed up for 3 months for prognosis information. The prevalences of risk factors were calculated, and their relationship with prognosis was analysed.ResultsAmong the investigated risk factors, hypertension (83.7%), hyperlipoidemia (56.6%), cigarette smoking (39.5%) and hyperglycemia (39.5%) were the most prevalent ones. Patients with 0 to 7 risk factors accounted for 4.65%, 10.85%, 23.26%, 27.13%, 24.81%, 4.65%, 3.88% and 0.78% of the total, respectively, and most patients had hypertension and another one or more risk factors. NIHSS scores on admission, instead of vascular risk factors, were independently correlated with prognosis (OR=1.58, 95% CI, 1.28－1.96). Conclusion Risk factors in patients with anterior circulation ischemic stroke or PCS are similar, and should be controlled in patients with PCS. Risk factors have impact on the incidence of PCS, while do not determine the prognosis of patients.

Key words: ischemic stroke, posterior circulation, risk factor, prognosis