上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (11): 1647-.doi: 10.3969/j.issn.1674-8115.2011.11.031

• 综述 • 上一篇    下一篇

肿瘤标志物检测技术的应用和进展

赵士艳1, 聂秀利1, 刘兴党2, 管 樑3, 严惟力1   

  1. 1.上海交通大学 医学院附属仁济医院核医学科, 上海 200127； 2．复旦大学附属华山医院核医学科, 上海 200040|3.上海交通大学 医学院附属瑞金医院核医学科, 上海 200025
  • 出版日期:2011-11-28 发布日期:2011-11-29
  • 通讯作者: 严惟力, 电子信箱: yan_weili@hotmail.com。
  • 作者简介:赵士艳（1987—）, 女, 硕士生；电子信箱: vanilla0306@163.com。
  • 基金资助:

    国家自然科学基金(30770599) ；上海教委科技创新项目（09YZ82）

Application and advances of detection technology for tumor markers

ZHAO Shi-yan1, NIE Xiu-li1, LIU Xing-dang2, GUAN Liang3, YAN Wei-li1   

  1. 1.Department of Nuclear Medicine, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China；2.Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China；3.Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2011-11-28 Published:2011-11-29
  • Supported by:

    National Natural Science Foundation of China, 30770599；Shanghai Education Committee Foundation, 09YZ82

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摘要：

肿瘤尤其是恶性肿瘤严重威胁着人类的健康，肿瘤标志物（TM）的检测对恶性肿瘤的早期诊断、后期治疗有着重要的意义。随着细胞生物学和分子生物学的发展，TM及其应用已成为临床肿瘤诊断与研究的热点。TM检测技术的合理应用和结果是否准确，可直接影响肿瘤诊断和治疗的效果。文章就TM检测技术的应用和进展进行综述。

关键词: 肿瘤标志物, 检测技术, 标记免疫, 生物芯片

Abstract:

Malignant tumors have been threatening the human health critically, and the detection of tumor markers plays an important role in the early diagnosis and following treatment of malignant tumors. With the advances in cellular and molecular biology, the tumor markers and their application have become the hot spot of tumor diagnosis and research in clinics. The rational use of detection technology for tumor markers has direct effect on diagnosis and treatment of tumors. The application and advances of detection technology for tumor markers are reviewed in this paper.

Key words: tumor marker, detection technology, labeled immunoassays, biological chip