上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (5): 676-.doi: 10.3969/j.issn.1674-8115.2011.05.032

• 综述 • 上一篇    下一篇

子癎前期-子癎并发症发生机制的研究

乐怡平, 林建华   

  1. 上海交通大学 医学院附属仁济医院妇产科, 上海 200127
  • 出版日期:2011-05-28 发布日期:2011-05-27
  • 作者简介:乐怡平（1986—）, 女, 硕士生；电子信箱: leyiping_0@163.com。

Pathogenesis of complications of pre-eclampsia and eclampsia

LE Yi-ping, LIN Jian-hua   

  1. Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2011-05-28 Published:2011-05-27

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摘要：

子前期是妊娠期特有疾病之一，以妊娠期高血压和蛋白尿为主要临床表现，如不进行有效治疗，可进一步发展为子，并可产生心血管、肾脏、脑、血液、消化等各系统的严重并发症，严重威胁孕产妇及新生儿的生命。子前期发病机制尚未完全明确，目前认为胎盘低灌注是其病理基础，引起母体血管内皮细胞损伤，从而导致全身各系统功能障碍。文章主要对子前期子并发症的发生机制、发病率以及研究进展进行综述。

关键词: 子前期, 子, 并发症

Abstract:

Pre-eclampsia is a disorder that is unique to pregnancy, with gestational hypertension and proteinuria as main clinical manifestations. Without proper management, pre-eclampsia may develop to eclampsia and cause a series of complications involving cardiovascular, renal, neurologic, hematologic and gastrointestinal systems, which may threaten lives of mothers and infants. The pathogenesis of pre-eclampsia is still unclear, and reduced placental perfusion is considered to be the pathological mechanism, which may result in endothelial cell injury and further aggravate dysfunction of maternal systems. This paper reviews the pathogenesis, incidence and research progress of complications of pre-eclampsia and eclampsia.

Key words: pre-eclampsia, eclampsia, complication