上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (9): 1072-.doi: 10.3969/j.issn.1674-8115.2010.09.013

• 专题报道（影像医学与核医学） • 上一篇    下一篇

18F-FDG PET和PET/CT评估肿瘤新辅助化疗效果的应用进展

张 敏, 综述；李 彪, 审校   

  1. 上海交通大学 医学院附属瑞金医院核医学科, 上海 200025
  • 出版日期:2010-09-25 发布日期:2010-09-27
  • 作者简介:张 敏（1981—）, 男, 住院医师, 硕士；电子信箱: zmjacques@hotmail.com。
  • 基金资助:

    上海市重点学科建设项目(S30203)

Progress of application of 18F-FDG PET and PET/CT in assessment of response of tumor to neoadjuvant chemotherapy

ZHANG Min, reviewer；LI Biao, reviser   

  1. Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2010-09-25 Published:2010-09-27
  • Supported by:

    Shanghai Leading Academic Discipline Project, S30203

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摘要：

新辅助化疗在临床肿瘤治疗中的应用日益普遍，利用18F氟脱氧葡萄糖（18F-FDG）正电子发射断层扫描（PET）和PET/CT可早期评估新辅助化疗效果，有助于肿瘤再分期、合理选择化疗药物以及判断预后，对制定患者的治疗方案和减少无效治疗具有临床指导意义。文章就18F-FDG PET和PET/CT评估肿瘤新辅助化疗效果的应用进展进行综述。

关键词: 正电子发射断层扫描, 18F氟脱氧葡萄糖, 肿瘤, 新辅助化疗

Abstract:

Neoadjuvant chemotherapy is increasingly widely used in the treatment of cancer, and 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) and PET/CT play a role in the early assessment of response to neoadjuvant chemotherapy, including tumor restaging, drug selection and prognosis prediction, which facilitate the design of therapeutic regimen and reduction of ineffective therapy.The progress of application of 18F-FDG PET and PET/CT in the assessment of response of tumor to neoadjuvant chemotherapy is reviewed in this paper.

Key words: positron emission tomography, 18F-fluorodeoxyglucose, tumor, neoadjuvant chemotherapy