上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (6): 824-.doi: 10.3969/j.issn.1674-8115.2011.06.032

• 论著（临床研究） • 上一篇    下一篇

中老年男性高血压患者勃起功能障碍相关因素分析

张佳卉1, 杨海芸1, 周 慧1, 李 铮2   

  1. 上海交通大学 医学院附属仁济医院 1.普内科, 2.泌尿外科, 上海 200001
  • 出版日期:2011-06-28 发布日期:2011-06-27
  • 通讯作者: 杨海芸, 电子信箱: yanghaiyun731031@126.com。
  • 作者简介:张佳卉(1980—), 女, 住院医师, 硕士生；电子信箱: jhuizh@hotmail.com。

Analysis of related factors for erectile dysfunction in middle-aged and elderly patients with hypertension

ZHANG Jia-hui1, YANG Hai-yun1, ZHOU Hui1, LI Zheng2   

  1. 1.Department of Internal Medicine, 2.Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China
  • Online:2011-06-28 Published:2011-06-27

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摘要：

目的 探讨中老年男性高血压患者勃起功能障碍（ED）的相关因素。方法 选择257例40～70岁男性原发性高血压患者，记录其年龄、高血压病程、血压、有无靶器官损伤、体质量指数和腰围等情况，采用国际勃起功能指数-5评估勃起功能，抑郁自评量表（SDS）评估抑郁状态及严重程度，单因素和多因素Logistic回归分析ED与相关因素的关系。结果 257例原发性高血压患者中ED 188例（73.15%），ED患者SDS评分（47.49±10.74）显著高于国内常模（41.88±10.57）（P<0.01）。Logistic回归分析显示：中年男性（40～59岁）高血压患者病程、脉压、靶器官损伤、抑郁程度与ED的关联有统计学意义（P<0.05）；老年男性（60～70岁）高血压患者病程、脉压与ED的关联有统计学意义（P＝0.00）。结论 高血压病程长、脉压大且伴有靶器官损伤和抑郁的中老年男性需考虑ED的可能性。

关键词: 勃起功能障碍, 高血压, 抑郁

Abstract:

Objective To explore the related factors for erectile dysfunction (ED) in middle-aged and elderly patients with hypertension. Methods Two hundred and fifty-seven patients with essential hypertension aged between 40 to 70 years were selected, the data of age, duration of hypertension, blood pressure, status of hypertensive target organs, body mass index and waist circumference were recorded, the erectile function was evaluated by International Index of Erectile Function-5, the status and severity of depression were investigated by Self-rating Depression Scale(SDS), and univariate and multivariate Logistic regression analyses were employed to explore the relationship between ED and related factors. Results There were 188 patients (73.15%) with ED in all the 257 patients, and the SDS score of patients with ED (47.49±10.74) was significantly higher than that of Chinese norm (41.88±10.57)(P<0.01). Logistic regression analyses revealed that duration of hypertension, pulse pressure, status of hypertensive target organs and depression were significantly related to ED in middle-aged patients (40 to 59 years old) with hypertension (P<0.05), and duration of hypertension and pulse pressure were significantly related to ED in elderly patients (60 to 70 years old) with hypertension (P=0.00). Conclusion The chance of ED should be considered in patients with long duration of hypertension, high pulse pressure, hypertensive target organ damage and depression.

Key words: erectile dysfunction, hypertension, depression