上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2018, Vol. 38 ›› Issue (7): 775-.doi: 10.3969/j.issn.1674-8115.2018.07.010

• 论著·临床研究 • 上一篇    下一篇

病程12个月及以上非小细胞肺癌患者生活质量评估及影响因素研究

何亚平 1，楼玮群 2，陈杰灵 2，周箴 3，朱静芬 1，简红 3   

  1. 1. 上海交通大学公共卫生学院，上海200025；2. 上海交通大学附属胸科医院上海市胸科医院肿瘤科，上海200030；3. 香港大学社会工作与社会行政学系，香港
  • 出版日期:2018-07-28 发布日期:2018-07-30
  • 作者简介:何亚平（1964—），女，副教授，博士；电子信箱：hypcyr@sina.com。
  • 基金资助:
    上海市卫生和计划生育委员会科研项目（201740116）；上海交通大学医学院教育研究重点项目（ZD150603）

Influencing factors for quality of life in patients over 12 months after diagnosis of non-small cell lung cancer

HE Ya-ping1, LOU Wei-qun2, CHEN Jie-ling2, ZHOU Zhen3, ZHU Jing-fen1, JIAN Hong3   

  1. 1. School of Public Health, Shanghai Jiao Tong University, Shanghai 200025, China; 2. Department of Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China; 3. Department of Social Work & Social Administration, The University of Hong Kong, Hong Kong, China
  • Online:2018-07-28 Published:2018-07-30
  • Supported by:
    Shanghai Municipal Health and Family Planning Commission Foundation, 201740116; Shanghai Jiao Tong University School of Medicine Core Education Project, ZD150603

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摘要： 目的·评估首诊至调查时间病程≥12个月的非小细胞肺癌（non-small cell lung cancer，NSCLC）患者的生活质量，探讨相关影响因素。方法·采用FACT-L（Functional Assessment of Cancer Therapy–Lung）量表对111名纳入研究的患者的生活质量进行评价，自制问卷收集患者人口学特征、医疗信息和情绪感受。结果·研究从治疗及患者主观感受2个路径探讨NSCLC患者生活质量的影响因素。单因素Logistic回归分析显示低生活质量的风险因素为：自卑孤独感、骨转移、病理类型、化学治疗周期、年龄、共住家庭成员结构和经济困难。结论·肺癌患者生活质量影响因素多元而广泛，情绪及症状管理亟待重视。

关键词: 非小细胞肺癌, 生活质量, 影响因素

Abstract:

Objective · To examine quality of life and its influencing factors in patients over 12 months after diagnosis of non-small cell lung cancer (NSCLC). Methods · A total of 111 patients included in the study completed the self-reported measures. Quality of life was measured using Functional Assessment of Cancer Therapy–Lung. Other measures included socio-demographic characteristics, disease- and treatment-related information, and emotional feelings. Results · The factors influencing the quality of life of NSCLC patients were investigated two approaches: treatment and subjective feeling. Univariate Logistic regression analysis found the risk factors for low quality of life included sense of low self-esteem and loneliness, bone metastasis, pathological type, chemotherapy cycle, age, cohabitant type and financial burden. Conclusion · The factors associated with quality of life in lung cancer patients are diverse and extensive, and it warrants attention on psychological support and symptom management for these patients.

Key words: non-small cell lung cancer, quality of life, influencing factor

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