上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2019, Vol. 39 ›› Issue (10): 1199-.doi: 10.3969/j.issn.1674-8115.2019.10.017

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肠道菌群在抑郁症、焦虑症及物质使用障碍中的作用

宋月红，江海峰，彭素芳，赵 敏   

  1. 上海交通大学医学院附属精神卫生中心，上海201108
  • 出版日期:2019-10-28 发布日期:2019-11-22
  • 作者简介:宋月红（1979—），女，主治医师，学士；电子信箱：scouyz@163.com。
  • 基金资助:
    国家重点研发计划（2017YFC1310400）；上海市科技重大专项（2018SHZDZX05）；上海市优秀学术/技术带头人计划（17XD1403300）

Research progress of gut microbiota in depression, anxiety and substance disorders

SONG Yue-hong, JIANG Hai-feng, PENG Su-fang, ZHAO Min   

  1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 201108, China
  • Online:2019-10-28 Published:2019-11-22
  • Supported by:
    National Key Research and Development Plan, 2017YFC1310400; Shanghai Municipal Science and Technology Major Project, 2018SHZDZX05； Shanghai Excellent Academic/Technical Leader Program, 17XD1403300

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摘要： 目前大量研究证明神经-肠-脑轴在精神疾病中的重要作用，关注肠道菌群与精神疾病的相互关系和可能的调控机制。该文对几种关注较多的精神疾病，如抑郁症、焦虑症和物质使用障碍中肠道菌群的研究现状进行了总结，以期为肠道菌群成为治疗新靶点提供更多的临床证据。

关键词: 肠道菌群, 神经-肠-脑轴, 抑郁症, 焦虑症, 物质使用障碍

Abstract:

At present, a large number of studies have proved the important role of the nerve-gut-brain axis in mental disorders, and focused on the correlation between gut microbiota and mental disorders and the potential regulating mechanisms. This paper summarizes the current research status of gut microflora in several mental disorders, such as depression, anxiety and substance disorders, into provide more clinical evidence for gut microflora as a new target for treatment.

Key words: gut microbiota, nerve-gut-brain axis, depression, anxiety, substance disorders

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