上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (9): 1043-.doi: 10.3969/j.issn.1674-8115.2010.09.006

• 专题报道（影像医学与核医学） • 上一篇    下一篇

18F-FDG PET/CT意外发现胃肠道局限性高代谢灶的临床意义

张 淼1, 陈 刚1, 王 超1, 胡佳佳1, 张 敏1, 徐昊平1, 鲍昭芳2, 李 彪1   

  1. 上海交通大学 |医学院附属瑞金医院 1.核医学科, 2.特需门诊, 上海 200025
  • 出版日期:2010-09-25 发布日期:2010-09-27
  • 通讯作者: 李 彪, 电子信箱: lb10363@rjh.com.cn。
  • 作者简介:张 淼（1977—）, 女, 主治医师, 博士；电子信箱: laurazm_cn@sina.com。
  • 基金资助:

    上海市重点学科建设项目(S30203)

Clinical value of 18F-FDG PET/CT in detection of unexpected gastrointestinal lesions with high uptake

ZHANG Miao1, CHEN Gang1, WANG Chao1, HU Jia-jia1, ZHANG Min1, XU Hao-ping1, BAO Zhao-fang2, LI Biao1   

  1. 1.Department of Nuclear Medicine, 2.Exclusive Medical Care Centre, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2010-09-25 Published:2010-09-27
  • Supported by:

    Shanghai Leading Academic Discipline Project, S30203

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摘要：

目的 探讨18F-FDG PET/CT意外发现胃肠道局限性高代谢灶的临床意义。方法 回顾性分析4 188例进行18F-FDG PET/CT检查的病例，选择满足以下条件的病例作为研究对象：18F-FDG PET/CT 检查中意外发现胃肠道局限性高代谢灶怀疑为恶性肿瘤，且在18F-FDG PET/CT检查前无相应部位的临床症状或影像学异常。共有45例病例入选，将PET/CT检查结果与病理结果进行对照。结果 4 188例被检者中意外发现胃肠道高代谢灶45例（1.1%），失访5例，经病理证实异常者40 例。其中恶性病变23例（57.5%），良性病变（癌前病变）2例（5%），炎性病变15例（37.5%）。胃肠道肿瘤组的SUVmax值为（9.8±4.5），高于炎症病变组的SUVmax值（6.5±2.5），差异有统计学意义（P<0.05）。结论 18F-FDG PET/CT意外发现的胃肠道局限性高代谢灶恶性肿瘤的可能性较大，需要给予足够的重视，对于无症状胃肠道肿瘤的早期发现和及时诊治具有重要意义。

关键词: 正电子发射型体层摄影, 胃肠道, 肿瘤

Abstract:

Objective To explore the clinical value of 18F-FDG PET/CT in detection of unexpected gastrointestinal lesions with high uptake. Methods The clinical data of 4 188 patients examined by 18F-FDG PET/CT were retrospectively analysed. Patients with unexpected gastrointestinal lesions with high uptake suspected of malignant tumors examined by 18F-FDG PET/CT, and without corresponding clinical symptoms and imaging abnormalities were selected. Forty-five out of 4 188 patients were enrolled, and the results of PET/CT examinations were compared with pathological findings. Results Unexpected gastrointestinal lesions with high uptake were detected in 45 out of 4 188 patients (1.1%). Among the 45 patients, 40 were confirmed by pathological examinations, and the other 5 were lost to follow up. Among the 40 patients, there were 23 cases (57.5%) of malignant lesions, 2 cases (5%) of benign lesions (precancerous lesions) and 15 cases (37.5%) of inflammatory lesions. SUVmax of gastrointestinal tumors group (9.8±4.5) was significantly higher than that of inflammatory lesions group （6.5±2.5）(P<0.05). Conclusion The possibility of unexpected gastrointestinal lesions with high uptake detected by 18F-FDG PET/CT to be malignant ones is higher, and attention should be paid to the early detection and timely treatment of gastrointestinal tumors without symptoms.

Key words: position emission tomography, gastrointestinal tract, oncology