上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (8): 1189-.doi: 10.3969/j.issn.1674-8115.2011.08.031

• 综述 • 上一篇    下一篇

巨噬细胞活化与创面愈合

缪明远, 牛轶雯, 陆树良   

  1. 上海交通大学 医学院附属瑞金医院灼伤整形科 上海市烧伤研究所, 上海 200025
  • 出版日期:2011-08-28 发布日期:2011-08-29
  • 作者简介:缪明远（1984—）, 男, 博士生；电子信箱: mmy0201121@gmail.com。
  • 基金资助:

    国家自然科学基金（30570705, 30600645）；上海交通大学医学院博士创新基金（BXJ201016）

Macrophage activation and wound healing

MIAO Ming-yuan, NIU Yi-wen, LU Shu-liang   

  1. Shanghai Burn Institute, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2011-08-28 Published:2011-08-29
  • Supported by:

    National Natural Science Foundation of China, 30570705, 30600645；Doctorate Innovation Fund of Shanghai Jiaotong University School of Medicine, BXJ2010016

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摘要：

巨噬细胞在创面愈合中扮演重要角色。巨噬细胞活化状态是其执行功能的主要工作状态，近年的研究表明巨噬细胞具有经典巨噬细胞活化和替代性巨噬细胞活化两种活化方式。创面中巨噬细胞所呈现的不同活化状态影响了创面修复的结局。该文就巨噬细胞活化及其与创面愈合的关系进行综述。

关键词: 巨噬细胞, 活化, 创面修复

Abstract:

Macrophages play a vital role in wound healing. Macrophage activation is the main status for working, and recent studies have demonstrated that macrophage activation could be divided into classical macrophage activation and alternative macrophage activation. The phenotypes of macrophage in wound tissues lead to different outcomes of cutaneous repair. This paper discusses macrophage activation and the relation with wound healing.

Key words: macrophage, activation, wound healing