上海交通大学学报(医学版)

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妊娠期妇女贫血及体内相关微量营养物水平的调查和分析

杨 亭1,2,谷 燕1,魏小平1,梁小华1,曹骄阳1,陈 洁1,刘友学1,张 霆3,李廷玉1   

  1. 1.重庆医科大学附属儿童医院儿童营养研究室, 重庆 400014; 2.重庆医科大学公共卫生与管理学院,重庆 400016; 3.首都儿科研究所, 北京 100020
  • 出版日期:2014-04-28 发布日期:2014-05-13
  • 通讯作者: 李廷玉, 电子信箱: tyli@vip.sina.com。
  • 作者简介:杨 亭(1987—), 女, 硕士生; 电子信箱: tingyang1206@126.com。

Investigation and analysis of anemia and levels of related micronutrients during gestation period

YANG Ting1,2, GU Yan1, WEI Xiao-ping1, LIANG Xiao-hua1, CAO Jiao-yang1, CHEN Jie1, LIU You-xue1, ZHANG Ting3, LI Ting-yu1   

  1. 1.Children's Nutritional Research Center, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; 2.College of Public Health and Management, Chongqing Medical University, Chongqing 400016, China; 3.Capital Institute of Pediatrics, Beijing 100020, China
  • Online:2014-04-28 Published:2014-05-13

摘要:

目的 对妊娠期妇女贫血及相关微量营养物水平进行调查,分析妊娠期不同阶段贫血对新生儿体格指标的影响。方法 选取重庆市铜梁县299名孕妇作为调查对象,抽取空腹静脉血样,对血红蛋白及贫血相关微量营养物进行检测,并对妊娠结局及新生儿体格指标进行随访。结果 299名孕妇中,维生素A缺乏、边缘性维生素A缺乏、铁缺乏和维生素B12缺乏的发生率分别为11.0%(33/299)、43.8%(131/299)、5.7%(17/299)和0.3%(1/299);妊娠贫血的发生率为24.5%(62/253)。孕早期贫血组孕妇血浆维生素A和铁浓度显著低于非贫血组(P<0.05);孕晚期贫血组新生儿出生体质量显著低于非贫血组(P<0.05)。结论 重庆市铜梁县妊娠贫血及妊娠期维生素A和铁缺乏的发生率较高,需加强孕期营养饮食指导,及时治疗,以保证母婴健康。

关键词: 贫血, 维生素A, 维生素B12, 铁, 妊娠期

Abstract:

Objective To investigate the anemia and levels of related micronutrients of pregnancy women and analyze the effects of anemia at different stages of gestation on physical indexes of neonates. Methods The fasting venous blood of 5 mL was drawn from 299 pregnancy women of Tongliang Country, Chongqing for detecting the hemoglobin and micronutrients related to anemia. The pregnancy outcomes and physical indexes of neonates were followed up. Results Among 299 pregnant women, the rates of vitamin A deficiency, marginal vitamin A deficiency, iron deficiency, and vitamin B12 deficiency were 11.0% (33/299), 43.8% (131/299), 5.7% (17/299), and 0.3% (1/299), respectively. The incidence of anemia during gestation period was 24.5%(62/253). The levels of plasma vitamin A and iron of early pregnancy anemia group were significant lower than those of non-anemia group (P<0.05). The birth weights of neonates of late pregnancy anemia group were statistically lower than those of non-anemia group (P<0.05). Conclusion The incidences of anemia, vitamin A deficiency, and iron deficiency during gestation period are still high in Tongliang Country, Chongqing. The guidance of gestation dietary should be strengthened and the anemia should be treated in time so as to ensure the health of both mothers and fetuses.

Key words: anemia, vitamin A, vitamin B12, iron, gestational period