上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (9): 1332-.doi: 10.3969/j.issn.1674-8115.2011.09.028

• 综述 • 上一篇    下一篇

小儿先天性心脏病手术前大脑损伤的研究进展

唐嘉忠, 王 伟   

  1. 上海交通大学 医学院附属上海儿童医学中心胸心外科, 上海 200127
  • 出版日期:2011-09-28 发布日期:2011-09-27
  • 通讯作者: 王 伟, 电子信箱: wangweicpb@hotmail.com。
  • 作者简介:唐嘉忠(1983—), 男, 住院医师, 学士；电子信箱: tangjiazhong@hotmail.com。

Research progress of pre-operative brain injury in children with congenital heart disease

TANG Jia-zhong, WANG Wei   

  1. Department of Cardiovascular and Thoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2011-09-28 Published:2011-09-27

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摘要：

先天性心脏病患儿手术后存在大脑损伤，既往认为大脑损伤与外科手术操作和体外循环等有关，目前发现先天性心脏病患儿手术前即可存在大脑损伤。文章结合国内外小儿先天性心脏病大脑损伤研究的最新进展，系统综述小儿先天性心脏病大脑损伤的基本类型、术前大脑损伤的流行病学及其可能的发病机制。

关键词: 先天性心脏病, 大脑损伤

Abstract:

Brain injury may occur in children after surgery for congenital heart disease, and brain injury was considered to be associated with surgical procedures and cardiopulmonary bypass. However, it has been reported that brain injury may exist in children with congenital heart disease before surgery. This paper systematically summarizes the basic types of brain injury and epidemiology and possible pathogenesis of brain injury before surgery in children with congenital heart disease.

Key words: congenital heart disease, brain injury