›› 2011, Vol. 31 ›› Issue (11): 1643-.doi: 10.3969/j.issn.1674-8115.2011.11.030

• Review • Previous Articles     Next Articles

Research progress of DNA methylation in schizophrenia

ZHANG Chen, YI Zheng-hui, FANG Yi-ru   

  1. Department of Mood Disorder, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, China
  • Online:2011-11-28 Published:2011-11-29
  • Supported by:

    National Natural Science Foundation of China, 30971047, 81000581;National High Technology Research and Development Program of China, “863” Program, 2006AA02Z430;Shanghai Natural Science Foundation, 10ZR1425700;Shanghai Municipal Health Bureau Foundation, 2009Y051;Shanghai Jiaotong University School of Medicine Foundation, 2008-6


Environmental factors play an important role in the etiology of schizophrenia. Recent studies have found that environmental factors may regulate gene expression though DNA methylation, and enhance risk of schizophrenia. The role of DNA methylation in contribution of environmental factors to etiology of schizophrenia is reviewed in this paper.

Key words: DNA methylation, environmental factor, schizophrenia