上海交通大学学报(医学版) ›› 2022, Vol. 42 ›› Issue (3): 282-289.doi: 10.3969/j.issn.1674-8115.2022.03.004

• 心脑血管慢病协防共管专题 • 上一篇    下一篇

上海社区老年人群队列心脑血管疾病单患、共患基线情况及生活方式特征

蒋惠如1(), 李峥1(), 马卓然2, 魏霖1, 袁安彩1, 胡刘华1, 陈潇雨3, 郭韵悦3, 张薇1(), 卜军1()   

  1. 1.上海交通大学医学院附属仁济医院心内科,上海 200127
    2.蚌埠医学院公共卫生学院,蚌埠 233030
    3.上海交通大学医学院附属仁济医院临床研究中心,上海 200127
  • 收稿日期:2022-01-29 出版日期:2022-03-28 发布日期:2022-05-09
  • 通讯作者: 张薇,卜军 E-mail:sunnyjiang1011@163.com;schoenlz@126.com;zhangwei050080@renji.com;pujun310@hotmail.com
  • 作者简介:蒋惠如(1994—),女,实习研究员,博士;电子信箱:sunnyjiang1011@163.com
    李 峥(1981—),男,主治医师,硕士;电子信箱:schoenlz@126.com第一联系人:为共同第一作者。
  • 基金资助:
    国家重点研发计划(2018YFC1312802);浦东新区卫生健康委员会联合攻关项目(PW2019D-11)

Baseline characteristics and lifestyle factors of single and co-morbidity of cardio-cerebrovascular diseases in Shanghai Community Elderly Cohort

Huiru JIANG1(), Zheng LI1(), Zhuoran MA2, Lin WEI1, Ancai YUAN1, Liuhua HU1, Xiaoyu CHEN3, Yunyue GUO3, Wei ZHANG1(), Jun PU1()   

  1. 1.Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
    2.School of Public Health, Bengbu Medical College, Bengbu 233030, China
    3.Center for Clinical Investigation, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Received:2022-01-29 Online:2022-03-28 Published:2022-05-09
  • Contact: Wei ZHANG,Jun PU E-mail:sunnyjiang1011@163.com;schoenlz@126.com;zhangwei050080@renji.com;pujun310@hotmail.com
  • Supported by:
    National Key R&D Program of China(2018YFC1312802);Joint Project of Health Committee of Pudong New Area(PW2019D-11)

摘要:

目的·基于大规模前瞻性社区老年人群队列,探索心脑血管疾病单患、共患人群的流行病学和危险因素特征。方法·研究的对象来源于上海社区老年人群队列。该队列的基线调查始于2019年2月,结束于2019年8月,收集了包括队列成员的人口统计学信息、疾病史和家族史、生活方式、心理状况等信息。根据自我报告有无冠状动脉性心脏病(冠心病)和/或脑卒中将全部队列成员分为4组:冠心病单患组、脑卒中单患组、心脑血管疾病(冠心病+脑卒中)共患组以及对照组(无冠心病及脑卒中)。对这4组对象的基本信息、共患其他疾病情况、生活方式、心理状况、睡眠状态等进行分析比较。结果·17 948名符合入选标准的研究对象纳入队列研究,其中冠心病单患组2 050名、脑卒中单患组724名、心脑血管疾病共患组269名、对照组14 905名。4组人群平均年龄分别为(70.4±6.2)岁、(71.8±7.1)岁、(73.2±7.0)岁和(68.3±5.9)岁。心脑血管疾病共患组患者合并高血压(76.6%)、高脂血症(38.3%)、糖尿病(26.0%)等基础性疾病的比例最高,其次为脑卒中单患组(分别为74.2%、26.8%和25.8%)、冠心病单患组(分别为72.9%、21.1%和21.7%),而对照组最低(分别为54.6%、8.7%和15.4%)。心脑血管疾病共患组患者有抑郁症状(16.0%)、焦虑症状(13.1%)、久坐习惯(2.2%)、睡眠质量较差或很差(38.6%)的比例最高,其次是脑卒中单患组(分别为10.1%、6.6%、2.2%和27.2%)、冠心病单患组(分别为7.9%、4.8%、0.5%和27.0%)。心脑血管疾病共患组患者有规律运动习惯的比例(29.5%)最低,而对照组的规律运动比例(39.2%)最高。结论·冠心病、脑卒中患者尤其是冠心病+脑卒中共患者合并基础性疾病、具有不良生活习惯和心理疾患的比例较高。

关键词: 冠状动脉性心脏病, 脑卒中, 队列, 生活方式

Abstract:

Objective·To explore the epidemiology and risk factors of single and co-morbidity of cardio-cerebrovascular diseases based on a large-scale prospective cohort of elderly people in the community.

Methods·The subjects of the study came from Shanghai Community Elderly Cohort. The baseline survey of this cohort began in February 2019 and ended in August 2019, collecting information including demographic information, diseases and family history, lifestyle and psychological status of cohort members. According to self-reported coronary heart disease and/or stroke, all cohort members were divided into four groups, which were single coronary heart disease group, single stroke group, cardio-cerebrovascular disease group (with both coronary heart disease and stroke), and control group (without coronary heart disease and stroke). Baseline information, disease history, lifestyle factors, psychological and sleep status among the four groups were analysed.

Results·A total of 17 948 eligible subjects participated in the cohort study, including 2 050 cohort members with single coronary heart disease, 724 cohort members with single stroke, 269 cohort members with cardio-cerebrovascular disease, and 14 905 cohort members without coronary heart disease and stroke. The average age of these four groups were (70.4±6.2) years, (71.8±7.1) years, (73.2±7.0) years and (68.3±5.9) years, respectively. The proportions of hypertension (76.6%), hyperlipidemia (38.3%) and diabetes (26.0%) were the highest in the cardio-cerebrovascular disease group, followed by the single stroke group (74.2%, 26.8% and 25.8%, respectively), and the single coronary heart disease group (72.9%, 21.1% and 21.7%, respectively), and the control group had the lowest proportion (54.6%, 8.7% and 15.4%, respectively). The proportions of depression symptoms (16.0%), anxiety symptoms (13.1%), sedentary habit (2.2%), and poor or fairly poor sleep (38.6%) in the cardio-cerebrovascular disease group were the highest, followed by the single stroke group (10.1%, 6.6%, 2.2% and 27.2%, respectively) and the single coronary heart disease group (7.9%, 4.8%, 0.5% and 27.0%, respectively). The proportion of regular exercise was the lowest in the cardio-cerebrovascular disease group (29.5%), while the proportion was the highest in the control group (39.2%).

Conclusion·Patients with coronary heart disease or stroke, especially those with both coronary heart disease and stroke, have a high proportion of co-morbidity with primary diseases, unhealthy lifestyles and psychological disorders.

Key words: coronary heart disease, stroke, cohort, lifestyle

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